MSC reverses opioid tolerance and opioid-induced hyperalgesia in rodents

Opioids are commonly prescribed to millions of patients for chronic pain. While they bring pain relief, they are associated with opioid tolerance (OT) - the body grows used to opioid medication and requires higher doses to manage pain adequately. Another condition associated with opioid use is opioid-induced hyperalgesia (OIH), where the patient grows even more [...]