This 2013 study features a treatment group (who received bone marrow mesenchymal stem cells) and a control group (who did not receive cells). 20 patients were in the treatment group and 20 in the control group, for a total of 40 patients with spinal cord injuries. The MSCs were harvested from the bone marrow of the participants. Only mild adverse events (fever and headache) were reported in the treatment group. Patients who did not receive cells showed no improvement after 6 months. Half (10/20) of those who received bone marrow MSC showed improvements in motor or sensory function, or in ASIA grades (9/20). The differences in scores between those who did not receive cells and those who did receive BMMSC were statistically significant.
Brain Res. 2013 Oct 2;1533:73-9. doi:10.1016/j.brainres.2013.08.016. Epub 2013 Aug 12.
Transplantation of autologous bone marrow mesenchymal stem cells in the treatment of complete and chronic cervical spinal cord injury.
Dai G, Liu X, Zhang Z, Yang Z, Dai Y, Xu R.