Newsletter June 2016
“I am bone on bone. Can stem stem cell therapy help me?”

Knee Pain Picture

“My doctor says that I am bone on bone. Can stem cell therapy help me?”

This is one of the most frequent questions people ask when they contact us about stem cell therapy for knee pain using our proprietary combination of bone marrow aspirate concentrate and *AlphaGEMS amniotic tissue product.

Many are under the false impression that because they are “bone on bone” that stem cell therapy cannot help them. Fortunately, this isn’t always the case. In fact, many patients who have been told they are “bone on bone” can benefit from stem cell therapy at RMI.

Theresa Hamrick’s Story

Teresa Hamrick was confined to a wheelchair with what her doctor told her was bone on bone arthritis. Now, one year after treatment at RMI, Teresa is walking again and her x-rays show increased spacing due to cartilage regrowth.

Video Thumbnail of Theresa Hamrick discussing stem cell therapy at RMITheresa Hamrick discusses her stem cell Journey

“It was bone on bone. There was almost no cartilage. What was there was in bad shape. I was in a wheelchair. I’m one year out and the x-rays look great. I’ve got cartilage again. I am out of the wheelchair and can walk again.” – Teresa Hamrick

(Discussion on knee treatment at RMI begins at 11:40 in video.)



How does AlphaGEMS enhance bone marrow stem cells?

Stem cell therapy at RMI combines a patient’s own bone marrow stem cells with proprietary AlphaGEMS amniotic membrane tissue product (from normal, healthy births) to treat bone, muscle, tendon, ligament and cartilage damage.

AlphaGEMS is composed of collagens and other structural proteins, which provide a biologic matrix that supports angiogenesis, tissue growth and new collagen production during tissue regeneration and repair.

The photographs below show the difference between a patient’s stem cells treated with AlphaGEMS and the same patient’s stem cells without.

The cells on the left have the morphology of young, healthy mesenchymal stem cells. No flattening, a red color of mitochondria, and they’re spread throughout the whole cell body. On the right, you’ll notice the cells that were not cultured with AlphaGEMS are flat and fibroblastic looking. They are becoming senescent, the last step before they stop producing growth signals and can do nothing but basically form scar tissue.

Cell With and Without AlphaGEMS2


Can stem cells fix an injured ACL (anterior cruciate ligament)?

One of the most common knee injuries is an anterior cruciate ligament sprain or tear.

Athletes who participate in high demand sports like soccer, football, and basketball are more likely to injure their anterior cruciate ligaments.

Several studies have shown that female athletes have a higher incidence of ACL injury than male athletes in certain sports.

Severity of the ACL injury, activity level and other factors determine whether non-surgical stem cell therapy or stem cell-enchanced surgery is the best option. Even when surgery is necessary, the addition of bone marrow aspirate concentrate and AlphaGEMS can significantly reduce recovery time and complications.

Jennifer Ziegler’s Story

Jennifer Ziegler Video ThumbJennifer Ziegler discusses her quick recovery from an ACL injury

“Using a bone marrow taken from my hip and AlphaGems, Dr. McKenna had me hiking, biking, walking and enjoying life after 1 month! Total recovery in 6 weeks! …So if you have a knee injury, back problems, or an orthopedic condition of any kind, I can’t recommend the Riordan-McKenna Institute enough!”
– Jennifer Ziegler



Woman Runner Yellow Knee Pain 600

Your Road to Recovery Starts Today!

To find out if you are a candidate for stem cell therapy at RMI, please complete this online medical history. It is the first step in our patient evaluation process. Once we receive it, our staff will contact you to guide you through the rest of the application process, which includes a telephone consultation with Dr. McKenna or another staff physician. If you live in the Dallas-Fort Worth area, you may make an appointment for an in-office evaluation with Dr. McKenna.



*AlphaGEMS tissue is donated after normal, healthy births.